Melatonin is a hormone your body produces naturally — released by the pineal gland as darkness falls to signal that it's time to sleep. When melatonin levels are disrupted by jet lag, shift work, late-night screens or simply getting older, falling asleep and staying asleep through the night can become a nightly struggle.

Natrol Advanced Sleep Maximum Strength delivers 10mg of melatonin in a two-layer controlled-release tablet. The outer layer releases 5mg quickly to help you fall asleep faster; the inner layer releases a further 5mg gradually through the night to support sustained sleep. Each tablet also includes 10mg of Vitamin B6 (as Pyridoxine HCl) to support your body's own melatonin production, and calcium. Natrol is the number one melatonin brand in America, and this 10mg formula is their maximum-strength sleep option — 100% drug-free and non-habit forming.

• Maximum strength 10mg melatonin in a two-layer controlled-release tablet
• 5mg immediate release to help you fall asleep faster; 5mg sustained release to help you stay asleep
• 10mg Vitamin B6 to support the body's natural melatonin production
• 100% drug-free
• Non-habit forming
• 100% Vegetarian
• Free from milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame

Research consistently shows that seven or more hours of quality sleep each night supports cognitive performance, emotional wellbeing, and overall health. For nights when restful sleep feels out of reach, Natrol Advanced Sleep 10mg Time Release offers a maximum-strength option designed to work with your body from the moment you close your eyes until morning.

What Is the Difference Between Immediate Release and Time Release Melatonin?

Immediate-release melatonin dissolves quickly and enters your system in a single burst, which can help you fall asleep but may wear off before morning. Time-release melatonin — like Natrol Advanced Sleep 10mg — uses a layered tablet structure to release melatonin in two stages: an initial dose for sleep onset and a sustained dose to support uninterrupted sleep through the night.

What Is the Right Melatonin Dose for Adults?

Melatonin doses in supplements typically range from 0.5mg to 10mg per serving. Lower doses (0.5mg–3mg) are often sufficient for mild sleep onset difficulties or jet lag; higher doses such as 5mg or 10mg are generally used for more significant sleep disruption or when a sustained-release effect is desired. As with any supplement, starting at the lowest effective dose is sensible — if you're unsure, speaking with your healthcare practitioner is a good first step.

Frequently Asked Questions

What is melatonin and how does it help with sleep?

Melatonin is a hormone produced naturally by the pineal gland that regulates your body's sleep-wake cycle. Levels rise in the evening as it gets dark, signalling to your body that it's time to wind down and sleep. Supplemental melatonin works by reinforcing this natural signal, helping you fall asleep at the right time.

How long before bed should I take Natrol Advanced Sleep 10mg?

As directed on the label: adults should take 1 tablet 30 minutes before bedtime. Because this is a time-release formula, you should expect to sleep for a full 8 hours — plan your timing accordingly.

Is Natrol Advanced Sleep 10mg suitable for vegetarians?

Yes. Natrol Advanced Sleep 10mg is 100% vegetarian. It is also free from milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame, making it suitable for people with a range of common dietary requirements.

What makes the two-layer tablet different from a standard melatonin tablet?

A standard melatonin tablet releases its entire dose at once, which may help you fall asleep but can wear off mid-sleep. The two-layer design in Natrol Advanced Sleep 10mg delivers a 5mg immediate-release dose for sleep onset, followed by a 5mg controlled-release dose that gradually disperses through the night — designed to support a full night's sleep rather than just the beginning of it.

Can I take Natrol Advanced Sleep if I use other medications?

If you are currently taking any medications — particularly tranquilisers, sedatives, or medications for autoimmune or depressive conditions — consult your healthcare professional before using this product. See the full warnings on the label for details.

Package Description: 60 Tablets

Serving Size: 1 Tablet

Number of Servings: 60

Other Ingredients: Microcrystalline cellulose, hypromellose, magnesium stearate, stearic acid, silicon dioxide, methylcellulose, glycerin.

No: milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame.

Adults, take 1 tablet 30 minutes before bedtime.

Not for use by children under 18 years of age. Not intended to diagnose or treat insomnia. If you take this product you may sleep for a full 8 hours. If you are under medical supervision or using any tranquilizers or sedatives, seek the advice of your healthcare professional prior to using. Consult your physician before using if you have an autoimmune condition, depressive disorder, or are pregnant or lactating. May cause drowsiness. Do not take when operating machinery or driving a vehicle. For occasional, short-term use only.

Store in a cool, dry place.
Keep out of reach of children.